Opposite Evolutionary Effects between Different Alternative Splicing Patterns
نویسندگان
چکیده
منابع مشابه
Alternative splicing expression of U1 snRNP 70K gene is evolutionary conserved between different plant species.
A U1-snRNP--specific 70K (U1-70K) protein is intricately involved in both constitutive and alternative splicing of pre-mRNAs. Here, we report cDNA and cognate genomic sequences of the U1-70K gene of maize and rice. The maize and rice U1-70K genes bear strong similarity to the Arabidopsis gene and each encode three transcripts in roots and shoots. Alternative splicing produces two transcripts fr...
متن کاملThe Evolutionary Relationship between Alternative Splicing and Gene Duplication
The protein diversity that exists today has resulted from various evolutionary processes. It is well known that gene duplication (GD) along with the accumulation of mutations are responsible, among other factors, for an increase in the number of different proteins. The gene structure in eukaryotes requires the removal of non-coding sequences, introns, to produce mature mRNAs. This process, know...
متن کاملPatterns of alternative splicing vary between species during heat stress
Plants have evolved a variety of mechanisms to respond and adapt to abiotic stress. High temperature stress induces the heat shock response. During the heat shock response a large number of genes are up-regulated, many of which code for chaperone proteins that prevent irreversible protein aggregation and cell death. However, it is clear that heat shock is not the only mechanism involved in the ...
متن کاملRole of Aberrant Alternative Splicing in Cancer
Alternative splicing can alter genome sequence and as a consequence, many genes change to oncogenes. This event can also affect protein function and diversity. The growing number of study elucidate the pathological influence of impaired alternative splicing events on numerous disease including cancer. Here, we would like to highlight the significant role of alternative splicing in cancer biolog...
متن کاملEvolutionary Conservation of Drosophila TAF1 Alternative Splicing
Alternative splicing is the process by which exons are differentially included in the mature mRNA. This mechanism regulates the production of functionally distinct proteins. In this study, I showed that the tissue-specific patterns of TAF1 pre-mRNA alternative splicing in Drosophila melanogaster are evolutionarily conserved in Drosophila virilis. This suggests that conserved TAF1 intronic and e...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Molecular Biology and Evolution
سال: 2007
ISSN: 0737-4038,1537-1719
DOI: 10.1093/molbev/msm072